The Body’s
Potential benefits of activating CB1 Receptors
- Lower anxiety
- Lower blood pressure
- Lower intestinal inflammation
- Relieve depression
- Reduce fear and paranoia
Potential benefits of activating CB2 Receptors
- Help with alcohol and nicotine addiction
- Increase appetite
- Neurodegenerative diseases
- Reduce chronic pain
- Reduce inflammation
- Stress Response
How CBD brings homeostasis to the human body
Central Nervous System
Facilitates the generation of new neurons and involved in neuroprotection regulation of motor activity, synaptic plasticity, and control of certain memory processing.
Immune System
Regulates the immune system by suppressing proinflammatory cytokine production.
Metabolism
Maintains balance by controlling food intake and metabolic functions such as energy storage, nutrient transport, and modulating insulin sensitivity.
Gastrointestinal System
Help protect GI Tract from inflammation and abnormally high gastric and enteric secretions.
Muscles
Enhances stamina by regulating blood sugar and encourages runner’s high.
Hormones
Plays a significant role in regulating metabolism, reproduction, and responses to stress.
Bones
Plays an important role in regulating bone mass and bone growth.
Links to Research Studies
CBC, CBD, CBDV, CBG, CBN, THCV
CBD
Link to Studies on Cannabidiol (CBD):
- CBD’s anti-anxiety properties / potential use for substance abuse disorders (British Journal of Pharmacology)
- Antitumor effects of CBD (National Library of Medicine)
- Antitumor activity on human breast carcinoma (National Library of Medicine)
- Anti-inflammatory, antioxidant properties of CBD (National Library of Medicine)
- Antiseizure properties of CBD (National Library of medicine)
- CBD in the treatment of post-traumatic stress disorder (PTSD) (National Library of Medicine)
- Chronic pain management (National Library of Medicine)
- Neuroprotective properties / oxidative stress / Alzheimer’s disease (Wiley Online Library)
- Anti-cancer / Anti-tumor potential (National Library of Medicine)
- Anxiety and Sleep (National Library of Medicine)
- Anti-bacterial properties (National Library of Medicine)
- Analgesic / myofascial pain relief (National Library of Medicine)Anti-bacterial properties
- Arthritis inflammation and pain (National Library of Medicine)
- Psoriasis / Inflammation relief (National Library of Medicine)
- Suppression of nausea and vomiting (National Library of Medicine)
CBD for Autism
Link to Studies on Cannabidiol (CBD) specific to autism:
- 80% of children with autism given CBD oil saw improvements. Amazingly, they had not seen improvements when taking pharmaceutical medications.
- 53 children with autism given CBD oil for a median duration of 66 days showed positive results.
- CBD for ADHD and autism. Five out of 10 participants also had seizure disorders. The study found improvements in all but one of the 15 autistic patients taking CBD oil.
CBDA
Link to Studies on cannabidiolic acid (CBDA):
- Journal of Natural Products: Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
- CBDA anti-nausea study (National Library of Medicine)
- CBDA study for reducing / preventing nausea, vomiting and anticipatory nausea (British Journal of Pharmacology)
- CBDA studied for similarities to nonsteroidal anti-inflammatory drugs (NSAIDS) (National Library of Medicine)
- CBDA studied for brain health (National Library of Medicine)
- CBDA studied for use against breast cancer (National Library of Medicine)
CBDV
Link to Studies on Cannabidivarin (CBDV):
- CBDV is currently being developed into a pharmaceutical drug designed to reduce or prevent seizures by GW Pharmaceuticals.
- CBDV is being studied as a potential treatment for some of the most significant issues related to autism spectrum disorder, including social functioning and communication, repetitive behaviors and cognitive problems.
- CBDV shows promise in aiding neurobehavioral issues associated with Rett syndrome. In this 2019 preclinical study, CBDV was found to be beneficial for memory, neurological and social deficits related to Rett syndrome.
- CBDV was found to reduce inflammation and enhance muscle function in this 2019 study on Duchenne muscular dystrophy (DMD).
- CBDV shows potential in reducing nausea in this study.
CBDV for Autism
Link to Studies on Cannabidivarin (CBDV) specific to autism:
- CBDV was recently shown to reduce motor impairments and cognitive deficits in animal models of Rett syndrome, a condition showing some degree of overlap with autism, raising the possibility that CBDV might have therapeutic potential in ASD.
- This study looked at the effects of CBDV on brain excitation and inhibition systems in adults with and without autism spectrum disorder.
- CBDV may normalize brain function in people with autism. An acute dose of CBDV modulated the brain chemistry in adult autistic patients toward neurotypical function.
- In this animal study, CBDV improved general health, sociability, motor coordination and normalized brain weight in a mouse model of Rett syndrome.
CBN
Link to Studies on Cannabinol (CBN):
- Analgesia / pain relief (National Library of Medicine)
- Analgesic / myofascial pain relief (National Library of Medicine)
- Cannabinol’s effects on man / sleep (National Library of Medicine)
- Anti-bacterial properties (National Library of Medicine)
- Anti-inflammatory properties / intestinal inflammation (British Journal of Pharmacology)
- Anti-cancer / Anti-tumor potential (National Library of Medicine)
- Effects on cultured human leukemia cells (National Library of Medicine)
- Antiepileptic / antiseizure properties (National Library of Medicine)
- Physiological / psychoactive study (National Library of Medicine)
- Psoriasis / Inflammation (National Library of Medicine)
- Reducing bacteria that causes oral cavities (Cureus)
- Delaying neurodegenerative disease (National Library of Medicine)
CBG
Links to Studies on Cannabigerol (CBG):
- Antibacterial activity against antibiotic-resistant MRSA
- anti-inflammatory properties
- antioxidant properties
- appetite stimulation
- bladder disfunction
- breast cancer
- chemotherapy-induced cachexia (weight loss and muscle wasting)
- colorectal cancer
- gastrointestinal cancer
- glioblastoma brain tumors
- Huntington’s disease
- inflammatory bowel disease (IBS)
- melanoma
- multiple sclerosis (MS)
- neuroinflammation
- pain relief
- Parkinson’s disease
THCV
Links to Studies on Tetrahydrocannabivarin (THCV):
- Appetite suppression / Food reward and aversion (International Journal of Neuropsychopharmacology)
- Therapeutic activity of THCV for obesity (National Library of Medicine)
- Potential treatment against obesity-associated glucose intolerance (National Library of Medicine)
- Potential treatment for obesity (British Journal of Pharmacology)
- Anti-nicotine anti-addiction effects (British Journal of Pharmacology)
- Anti-inflammatory properties (British Journal of Pharmacology)
- Antipsychotic effects / therapeutic potential for schizophrenia (British Journal of Pharmacology)
- Parkinson’s disease symptom relief (British Journal of Pharmacology)
- Neuroprotective properties for seizure, hypomobility, Huntington’s and Parkinson’s diseases (British Journal of Pharmacology)
CBC
Link to Studies on Cannabichromene (CBC):
- CBC and antidepressant effects (National Library of Medicine)
- CBC and antidepressant effects (British Journal of Pharmacology)
- Analgesic, anti-inflammatory, anti-cancer effects (National Library of Medicine)
- CBC and pain relief (National Library of Medicine)
- Anti-inflammatory properties (National Library of Medicine)
- Anti-inflammatory properties (National Library of Medicine)
- Anti-inflammatory / analgesic properties (British Journal of Pharmacology)
- Neural stem / progenitor cells / brain function (National Library of Medicine)
- Acne treatment (National Library of Medicine)
- Neuroprotective properties for seizure, hypomobility, Huntington’s and Parkinson’s diseases (British Journal of Pharmacology)